Erythema là gì

Author: Dr Cathy Yunjia Zhao, Dermatology Registrar, Westmead Hospital, Sydney, NSW, nước Australia. DermNet NZ Editor in Chief: Adjunct A/Prof Amandomain authority Oakley, Dermatologist, Hamilton, New Zealvà. Copy edited by Gus Mitchell/Maria McGivern. January 2019.

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What is erythema gyratum repens?

Erythema gyratum repens is a rare paraneoplastic type of annular erythema with a distinctive sầu figurate ‘wood-grain’ appearance. It has a svào association with malignancy.

Erythema gyratum repens-like eruption*
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*This patient"s rash had a wood-grain appearance like erythema gyratum repens but the rash was actually pemphigus foliaceus.

Who gets erythema gyratum repens?

Erythema gyratum repens is most often present in Caucasian men in their 60s. The male to female ratio is 2:1. There is an associated underlying malignancy in 80% of patients with erythema gyratum repens. Almost half of the patients with erythema gyratum repens have lung cancer (33–47%), & less commonly, oesophageal, breast, và stomach cancer <1,2>.

In rare cases, erythema gyratum repens has also been described in association with mycobacterial infections, connective sầu tissue diseases, & pregnancy <1>.


What causes erythema gyratum repens?

The svào association between erythema gyratum repens và malignancy has led lớn several different pathogenetic hypotheses. These hypotheses are described below.

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Recently, a link was proposed between cutaneous glutamine (a substance required for the proliferation of cells) và the multi-ring appearance of erythema gyratum repens <2>.

What are the clinical features of erythema gyratum repens?

Erythema gyratum repens presents with concentric erythematous rings that have a distinctive sầu wood-grain appearance. The rings progress in waves, with the leading edge migrating about 1 cm/day. A trailing or collarette scale may be seen. Erythema gyratum repens is very itchy.

The annular plaques most often involve sầu the limbs and trunk <1>.

How is erythema gyratum repens diagnosed?

Although erythema gyratum repens may be diagnosed clinically, a skin biopsy is often performed lớn exclude other conditions. The histological features of erythema gyratum repens are non-specific.

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Other investigations lớn be undertaken may include a complete blood count, biochemistry, antinuclear antibody profile, và malignancy screens (ie, chest X-ray, mammogram, cervical smear, tumour markers, computed tomography of the chest/abdomen/pelvis and, if indicated, endoscopy or colonoscopy) <1>.


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